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小剂量HB疫苗注射次数对产生HBsAb的研究
引用本文:罗志胜,古朝昆,苏春兰. 小剂量HB疫苗注射次数对产生HBsAb的研究[J]. 临床肝胆病杂志, 2002, 18(4): 256-256,F003
作者姓名:罗志胜  古朝昆  苏春兰
作者单位:右江民族医学院,广西,百色市,533000
摘    要:本文进行小剂量HB疫苗注射次数对诱导机体产生HBsAb的研究结果发现,注射第5针后,HBsAb阳转率为83.56%,与大剂量(10μg)3针免疫法的HBsAb阳转率86.67%相接近。男性HBsAb阳转率为82.05%,女性阳转率为85.29%。注射3针后,再继续注射第4针及第5针时,HBsAb阳转率均有所提高,但注射第6针后,HBsAb阳转率仍与第5针相似,由此可见,小剂量HB疫苗免疫预防注射,以注射到第5针为宜。

关 键 词:小剂量 HB疫苗 HBsAb 乙型肝炎
文章编号:1001-5256(2002)04-0256-02

A Study on the Injection Numbers of HB Vaccine with Small Dose Inducing Organism to Produce HBsAb
LUO Zhi-sheng,GU Chao-kun,SU Chun-lan. A Study on the Injection Numbers of HB Vaccine with Small Dose Inducing Organism to Produce HBsAb[J]. Chinese Journal of Clinical Hepatology, 2002, 18(4): 256-256,F003
Authors:LUO Zhi-sheng  GU Chao-kun  SU Chun-lan
Abstract:To study the relationship between the injection numbers of HB vaccine with small dose and HBsAb positive rate, our studies showed that it has similar positive conversion rate between five times injection with small dose (83 56%)and three times injection with big dose (86 67%). Positive conversion rate of HBsAb in male is 82 05% and in female is 85 29%. The fourth and fifth injection can improve the position conversion rate of HBsAb, but the sixth injection gets the similar rate with the fifth. So five times injection with small dose of HB Vaccine is better.
Keywords:HB Vaccine   Organism   HBsAb
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