| 延龄草属植物化学成分及药理作用研究进展 |
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| 引用本文： | 刘逸宇,杜江伟,屈春慧,李彦文,唐茂红,岳星男,李志勇.延龄草属植物化学成分及药理作用研究进展[J].中国现代中药,2024,26(5):889-902. |
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| 作者姓名： | 刘逸宇 杜江伟 屈春慧 李彦文 唐茂红 岳星男 李志勇 |
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| 作者单位： | 1.山西中医药大学 基础医学院，山西 晋中 030619;2.中国中医科学院 中药研究所，北京 100700;3.云南中医药大学 民族医药学院，云南 昆明 650504;4.山东中医药大学 中医学院，山东 济南 250301;5.中国中医科学院 中医药信息研究所，北京 100700;6.中央民族大学 药学院，北京 100081 |
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| 基金项目： | 国家自然科学基金面上项目（81473797）；中国中医科学院中药研究所基本科研业务费自主选题项目（ZXKT23009） |
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| 摘 要： | 延龄草属（Trillium L.）植物全世界约有50种，我国有3种，分别为吉林延龄草T.kamtschaticum Pall.、西藏延龄草T.govanianum Wall.和延龄草T.tschonoskii Maxim。延龄草属植物的主要化学成分为甾体皂苷类。现代药理学研究表明，药用延龄草属植物在抗癌、抗炎、镇痛、抗阿尔茨海默病、保肝、抗病原微生物、抗骨质疏松、抗氧化及改善心脑血管和消化系统疾病等方面具有显著作用。对国内外延龄草属植物的分布、化学成分、药理活性等进行系统综述，以期为延龄草属植物的深入研究和开发提供参考。
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| 关 键 词： | 延龄草属 化学成分 药理作用 甾体皂苷 |
| 收稿时间： | 2023/9/14 0:00:00 |
Research Progress on Chemical Constituents and Pharmacological Effects of Trillium L. |
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| LIU Yi-yu,DU Jiang-wei,QU Chun-hui,LI Yan-wen,TANG Mao-hong,YUE Xing-nan,LI Zhi-yong.Research Progress on Chemical Constituents and Pharmacological Effects of Trillium L.[J].Modern Chinese Medicine,2024,26(5):889-902. |
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| Authors: | LIU Yi-yu DU Jiang-wei QU Chun-hui LI Yan-wen TANG Mao-hong YUE Xing-nan LI Zhi-yong |
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| Institution: | 1.Basic Medical College, Shanxi University of Traditional Chinese Medicine, Jinzhong 030619, China;2.Institute of Chinese Materia Medica, China Academy of Chinese Medical Sciences, Beijing 100700, China;3.College of Ethnic Medicine, Yunnan University of Chinese Medicine, Kunming 650504, China;4.College of Traditional Chinese Medicine, Shandong University of Traditional Chinese Medicine, Ji''nan 250301, China;5.Institute of Information on Traditional Chinese Medicine, China Academy of Chinese Medical Sciences, Beijing 100700, China;6.School of Pharmacy, Minzu University of China, Beijing 100081, China |
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| Abstract: | There are about fifty species of Trillium L. in the world, three of which are in China, including T. kamtschaticum Pall., T. govanianum Wall., and T. tschonoskii Maxim. The main chemical constituents of Trillium L. are steroidal saponins. Modern pharmacological studies have shown that medicinal plants of Trillium L. have significant effects in anti-cancer, anti-inflammatory and analgesic, anti-Alzheimer''s disease, liver protection, anti-pathogenic microorganisms, anti-osteoporosis, anti-oxidation functions, and the alleviation of cardiovascular, cerebrovascular, and digestive systems. In this paper, the distribution, chemical constituents and pharmacological activities of Trillium L. in China and abroad have been systematically reviewed, so as to provide a reference for the in-depth research, development and utilization of Trillium L. |
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| Keywords: | Trillium L chemical constituents pharmacological effects steroidal saponins |
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