坦度螺酮固定剂量治疗社交焦虑症的临床评价 |
| |
引用本文: | 杨勇超,李爱玲,张中法,魏红强. 坦度螺酮固定剂量治疗社交焦虑症的临床评价[J]. 中国民康医学, 2014, 0(21): 20-22 |
| |
作者姓名: | 杨勇超 李爱玲 张中法 魏红强 |
| |
作者单位: | 河南省郑州市第八人民医院 |
| |
摘 要: | 目的:评价坦度螺酮治疗社交焦虑症的疗效和安全性。方法:用坦度螺酮和帕罗西汀进行随机双盲对照观察66例患者。采用Liebowitz社交焦虑量表(LSAS)、副反应量表(TESS)、临床总体印象量表(CGI)评价患者疗效和不良反应,并定期检查患者肝、肾功能、心电图、脑电图、血生化(Glu、K、Na、Cl)等。结果:坦度螺酮对社交焦虑症疗效与帕罗西汀相当,两组患者疗效分别为78.1%,79.4%,(P>0.05)。坦度螺酮的不良反应明显少于帕罗西汀(P<0.01)。结论:坦度螺酮是一种疗效较好、安全性较高的治疗社交焦虑症的药物。
|
关 键 词: | 坦度螺酮 帕罗西汀 社交焦虑症 |
Clinical evaluation of fixed-dose tandospirone in treatment of social anxiety disorder |
| |
Affiliation: | YANG Yong-chao;LI Ai-ling;ZHANG Zhong-fa;The Eighth People’s Hospital of Zhengzhou City; |
| |
Abstract: | Objective:To evaluate efficacy and safety of tandospirone in treatment of social anxiety disorder. Methods:66 so-cial anxiety disorder patients were divided into tandospirone and paroxetine for a random double-blind study. The efficacy and side effects were evaluated with Liebowitzs Social Anxiety Scale ( LSAS) , treatment emergent symptom scale ( TESS) , and clinical global impression scale ( CGI);and then renal function, liver function, electrocardiogram ( ECG) , electroencephalogram ( EEG) , biochemi-cal analysis ( Glu, K, Na, Cl) and the like were tested. Results:The clinical efficacy had no significant difference between tandospi-rone and paroxetine. The effective rates of two groups were separately 78. 1% and 79. 4% (P〉0. 05). The side effects of tandospirone were less than those of paroxetine (P〈0. 01). Conclusions: Tandospirone is an effective and highly safe drug in the treatment social anxiety disorder. |
| |
Keywords: | Tandospirone Paroxetine Social anxiety disorder |
本文献已被 CNKI 维普 等数据库收录! |
|