Uterine tumors resembling ovarian sex cord-stromal tumors: synchronous uterine tumors resembling ovarian sex cord-stromal tumors and ovarian sex cord tumor |
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Authors: | Abdullazade Samir Kosemehmetoglu Kemal Adanir Ilknur Kutluay Lale Usubutun Alp |
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Affiliation: | a Department of Pathology, Hacettepe University, 06100 Ankara, Turkey;b Department of Obstetrics and Gynecology, Hacettepe University, 06100 Ankara, Turkey;c Genel Pathology Center, 06440 Ankara, Turkey |
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Abstract: | Uterine tumors resembling ovarian sex cord-stromal tumors (UTROSCTs) are very rare. In this article, we present 3 cases that manifest classical histomorphological features alongside diverse immunohistochemical findings. As a distinctive finding, one of the patients had UTROSCT in the uterus and an ovarian sex cord tumor, called granulosa cell tumor, in the left ovary, simultaneously. Problems in diagnosing such pathologic condition generally arise because of the variable histologic picture of UTROSCT and may cause problems for general and other nongynecologic surgical pathologists. Immunohistochemically, these tumors express different markers that indicate their polyphenotypic origins. |
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Keywords: | Uterus UTROSCT Granulosa cell tumor Immunohistochemistry |
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