无缝线深板层角膜内皮移植术的研究进展

角膜内皮失代偿可严重影响视力,以往多采用的穿透性角膜移植手术(PKP)具有术后高度散光、移植片排斥等并发症,严重限制了术后视力的提高.如果能够单纯地进行后弹力层和内皮细胞层的移植,将减少手术操作所带来的受体角膜损伤并能更好地恢复术后视力.近年来,无缝线深板层角膜内皮移植手术的优点已逐渐获得公认;其中深板层角膜内皮细胞移植手术(DLEK)手术难度较大,限制了其在临床的广泛开展.而通过剥除受体角膜的后弹力层和内皮层来制作植床的角膜内皮移植手术即角膜后弹力层剥除内皮细胞移植手术(DSEK)已经取得了较好的手术效果.本文归纳、分析了DSEK的手术方法、效果及并发症等.

Sutureless deep lamellar endothelial keratoplasty

Corneal endothelial dysfunction can severely affect visual acuity.In order to deal with this morbidity, ophthalmologists used to perform penetrating keratoplasty, in which the complications, such as postoperative astigmatism and graft rejection,led to poor visual recovery.If only the Descemet's membrane and endothelium is transplanted, the corneal injury of recipients caused by surgeries would be reduced and better visual acuity recovery might be guaranteed.In the past few years, the advantages of sutureleas deep lamellar endothelial keratoplasty have been brought to the attention by more and more ophthalmologists worldwide.However, the challenging techniques of performing DLEK limits its chnical application.Other kind of, DSEK, by stripping Descemet's membrane and endothelium from the recipient cornea, has produced excellent outcomes.This article outlined and analysed surgery techniques, clinical results and complications of DSEK.