| ANCA相关性系统性血管炎的治疗进展 |
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| 引用本文： | 刘琳,龚莉. ANCA相关性系统性血管炎的治疗进展[J]. 内蒙古医学院学报, 2008, 30(6) |
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| 作者姓名： | 刘琳 龚莉 |
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| 作者单位： | 1. 天津南开大学,临床医学院,天津,300193
2. 内蒙古自治区医院,肾内科 |
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| 基金项目： | 内蒙古自治区教育厅自然科学研究(重点)(NJZZ07087) |
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| 摘 要： | ANCA相关性系统性血管炎是容易引起肾脏和肺脏等多器官严重损害的一组疾病，远期预后较差，及时采取有针对性的、合理的治疗是降低并发症，减轻肾脏损伤，改善预后的关键，也是一直以来相关专业的临床医师所期待解决的问题。本文介绍了近年来ANCA相关性系统性血管炎的治疗进展，特别是15-脱氧精胍菌素、TNF阻滞药、利妥昔单抗等针对不同靶点的治疗在临床的应用情况，期望为临床医师提供一些帮助。
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| 关 键 词： | 抗中性粒细胞胞质抗体 血管炎 治疗 |
ANCA-ASSOCIATED SYSTEMIC VASCULITIS:TREATMENT |
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| LIU Lin,GONG Li. ANCA-ASSOCIATED SYSTEMIC VASCULITIS:TREATMENT[J]. Acta Academiae Medicinae Neimongol, 2008, 30(6) |
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| Authors: | LIU Lin GONG Li |
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| Affiliation: | Medical College;Nankai University;Tianjin 300193 China |
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| Abstract: | The antineutrophil cytoplasmic antibody(ANCA)-associated systemic vasculitis(AASV) with its appalling prognosis is drawing international attention and effort in exploring its pathogenesis as well as satisfying treatment.The standard therapy-combination of corticosteroids and cyclophosphamide has dramatically advanced patient survival,however,the associated risk of relapse and severe,even life-threatening,treatment-related morbidity has caused wide concern,which is encouraging investigation of new approaches... |
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| Keywords: | antineutrophil cytoplasmic antibody vasculitis treatment |
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