2010年四川省甲型H1N1流感血清学调查

目的了解四川省人群甲型H1N1流感病毒抗体水平,为及时科学评估疫情发展趋势和完善防控策略与措施提供依据。方法按照国家方案采集不同年龄组人群血清标本,用血凝抑制(HI)试验方法进行抗体检测,HI抗体滴度≥1∶40判为阳性。结果四川省甲型H1N1流感阳性率17.39%(663/3 812);不同地区阳性率差异无统计学意义;6～17岁组阳性率最高(20.52%);男女性阳性率差异无统计学意义;就诊人群阳性率高于献血人群和体检人群,差异有统计学意义。结论四川省人群甲型H1N1流感阳性率较低,,甲型H1N1流感在人群中的自然感染未形成有效免疫屏障,甲型H1N1流感疫苗接种仍有必要。

Serological Survey of 2010 Pandemic Influenza A(H1N1) Virus Infection in Sichuan Province

Objective To understand the status of 2010 pandemic Influenza A(H1N1) virus infection in Sichuan province,provide evidence for scientific assessment of the epidemic trends in time and the improvement of prevention and control strategies and measures.Methods According to the national scheme,the blood samples were taken from the people in different age groups,and the antibody detection was conducted by hemagglutination-inhibition test,the HI antibody titer≥1:40 was regarded as positive.Results The positive rate of 2009 pandemic influenza A(H1N1) virus infection in Sichuan province was 17.39%(663/3 812).There was no statistical difference on the positive rate in different places.The positive rate of 6-17 age group was the highest(20.52%,).No significant difference on the positive rate was observed between males and females.The positive rate among outpatients was higher than blood donors and physical examination groups,with the difference statistically significant.Conclusion The positive rate of influenza A(H1N1) among population in Sichuan is not high,but natural infection in the population has not formed effective immune barrier,therefore,H1N1 vaccination is still necessary.