| 奥氮平与阿立哌唑治疗精神分裂症的临床研究 |
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| 引用本文： | 关德海. 奥氮平与阿立哌唑治疗精神分裂症的临床研究[J]. 中国民康医学, 2011, 23(18): 2231-2232. DOI: 10.3969/j.issn.1672-0369.2011.18.005 |
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| 作者姓名： | 关德海 |
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| 作者单位： | 辽宁省复员军人康宁医院,辽宁兴城,125100 |
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| 摘 要： | 目的:比较奥氮平与阿立哌唑治疗精神分裂症的疗效及安全性。方法:将60例精神分裂症患者随机分成两组,每组30例,分别给予奥氮平和阿立哌唑,疗程8周,采用阳性与阴性症状量表(PANSS)、临床疗效总评量表(CGI-SI)、治疗中出现的副反应量表(TESS)评定疗效和不良反应。结果:两组PANSS总分及CGI-SI评分均较治疗前显著下降(P<0.01),奥氮平组显效率77%,阿立哌唑组显效率73%,两组疗效相当(P>0.05)。奥氮平组嗜睡、体重增加的不良反应均明显高于阿立哌唑组(P<0.01),阿立哌唑组锥体外系反应、失眠、兴奋或激越明显高于奥氮平组(P<0.01)。结论:奥氮平与阿立哌唑治疗精神分裂症的疗效相当,奥氮平的安全性较高。
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| 关 键 词： | 奥氮平 阿立哌唑 精神分裂症 |
Clinical study of Olanzapine and Aripiprazole in the treatment of schizophrenia |
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| GUAN De-hai. Clinical study of Olanzapine and Aripiprazole in the treatment of schizophrenia[J]. medical journal of chinese peoples health, 2011, 23(18): 2231-2232. DOI: 10.3969/j.issn.1672-0369.2011.18.005 |
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| Authors: | GUAN De-hai |
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| Affiliation: | GUAN De-hai(Liaoning Emobilized Soldier Kangning Hospital,Xingcheng 125100,China) |
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| Abstract: | Objective:To compare the efficacy and safety of Olanzapine and Aripiprazole in the treatment of schizophrenia.Methods:60 patients with schizophrenia were randomly divided into two groups,each group of 30 cases,were given Olanzapine and Aripiprazole,treatment eight weeks,the curative effects and adverse reactions were assessed with PANSS,CGE-SI and TESS.Results:Two groups of PANSS total cent and CGE-SI scores were relatively before treatment significantly(P<0.01),Olanzapine group significat efficiency was 77... |
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| Keywords: | Olanzapine Aripiprazole Schizophrenia |
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