| 齐拉西酮对精神分裂症患者生活质量的影响 |
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| 引用本文： | 张晓南,李艳,杜茂盛,周文竹. 齐拉西酮对精神分裂症患者生活质量的影响[J]. 中国民康医学, 2011, 23(17): 2122-2123,2126. DOI: 10.3969/j.issn.1672-0369.2011.17.010 |
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| 作者姓名： | 张晓南 李艳 杜茂盛 周文竹 |
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| 作者单位： | 大连市第七人民医院,辽宁大连,116023 |
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| 摘 要： | 目的:探讨齐拉西酮对精神分裂症患者生活质量的影响。方法:80例精神分裂症患者随机平分为两组,分别给予齐拉西酮和利培酮治疗,疗程12周。采用阳性和阴性症状量表(PANSS)、不良反应量表(TESS)进行疗效、不良反应评定;采用生活质量量表(QOL-100)进行生活质量评估。结果:阿立哌唑与利培酮对精神分裂症的阳性症状、阴性症状的改善相似,PANSS评分两组间差异无统计学意义;齐拉西酮组不良反应发生率低于利培酮组;齐拉西酮组QOL-100各因子除精神支柱外均明显改善,在生理因子、心理因子、独立性因子、环境因子较利培酮组改善显著。结论:齐拉西酮治疗精神分裂症与利培酮的疗效相当,但不良反应少,能够显著改善患者的生活质量。
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| 关 键 词： | 齐拉西酮 利培酮 精神分裂症 疗效 生活质量 |
Influence of Ziprasidone on Quality on Life of Patients with Schizophrenia |
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| ZHANG Xiao-nan,LI Yan,DU Mao-sheng,et al. Influence of Ziprasidone on Quality on Life of Patients with Schizophrenia[J]. medical journal of chinese peoples health, 2011, 23(17): 2122-2123,2126. DOI: 10.3969/j.issn.1672-0369.2011.17.010 |
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| Authors: | ZHANG Xiao-nan LI Yan DU Mao-sheng et al |
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| Affiliation: | ZHANG Xiao-nan,LI Yan,DU Mao-sheng,et al(The No.7 People's Hospital of Dalian,Liaoning 116023,China) |
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| Abstract: | Objective:To investigate the efficacy of ziprasidone on life quality of patients with schizophrenia.Methods:Schizophrenic patienst who were treated by ziprasidone(n=30) or risperidone(n=30) were evaluated with positive and negative symptom scale(PANSS),treatment emergent symptom scale(TESS) and WHO Quality of Life-100(QOL-100) for 12 weeks.Results: The clinical efficacy had no significant difference between the two groups.The scores of PANSS in two groups after treatment were lower significantly than those ... |
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| Keywords: | Ziprasidone Resperdone Schizophrenia Efficacy Quality of life |
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