| 神经内科重症监护病房病原菌分布及药敏分析 |
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| 引用本文： | 李海英,李淑娟,胡文立,秦伟. 神经内科重症监护病房病原菌分布及药敏分析[J]. 实用全科医学, 2011, 0(10): 1631-1632 |
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| 作者姓名： | 李海英 李淑娟 胡文立 秦伟 |
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| 作者单位： | 首都医科大学附属北京朝阳医院神经内科; |
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| 摘 要： | 目的调查神经内科重症监护病房（NICU）感染患者的病原菌分布及耐药情况,以指导临床抗菌药物的应用,降低医院感染率。方法对2008年9月-2010年5月期间入住NICU的216例患者送检的痰、尿、便、血等451份标本进行病原菌鉴定和体外药敏试验。结果检出的399株病原菌中,G-杆菌140株,G＋球菌73株,真菌186株。病原菌主要来自于呼吸道。致病菌简单且集中,白色念珠菌和MRSA占所有致病菌的49.9%。药敏结果显示：真菌的临床耐药性较高,MRSA对糖肽类药物敏感性高,G-杆菌对碳青酶烯类药物敏感性高,G-杆菌对不同头孢类及青霉素类药物的敏感性差异较大。结论 NICU感染患者的主要病原菌为真菌及G-杆菌,可能与广谱类抗菌药物的大量使用有关。临床应减少广谱抗菌药物的应用,适当增加碳青酶烯类和糖肽类药物的使用,并推荐头孢哌酮/舒巴坦或头孢他啶作为常规用药。
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| 关 键 词： | 神经内科重症监护病房 药敏分析 病原菌 |
Characteristic Description and Drug Sensitivity Testing of Pathogenic Bacteria in Neurological Intensive Care Unit |
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| LI Hai-ying,LI Shu-juan,HU Wen-li,et al.. Characteristic Description and Drug Sensitivity Testing of Pathogenic Bacteria in Neurological Intensive Care Unit[J]. Applied Journal Of General Practice, 2011, 0(10): 1631-1632 |
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| Authors: | LI Hai-ying LI Shu-juan HU Wen-li et al. |
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| Affiliation: | LI Hai-ying,LI Shu-juan,HU Wen-li,et al.Department of Neurology,Beijing Chao-Yang Hospital,Affiliated to Capital Medical University,Beijing 100020,China |
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| Abstract: | Objective The characteristic of infection strains and the changes in antibiotic-resistance in neurological intensive care unit(NICU) were investigated to direct the antibiotics clinical application,and to reduce the hospital infection incidence rates.Methods From Sep.2008 to May 2010,451 species from 216 patients in NICU,including sputum,urine,stools,and blood,were cultured for bacteria identification and drug sensitivity testing.Results Among the isolated 399 strains of pathogenic bacteria,Gram-negative ba... |
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| Keywords: | Neurological intensive care unit(NICU) Drug sensitivity testing Pathogenic bacteria |
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