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HAG预激方案治疗低增生性急性髓细胞白血病临床研究
引用本文:韩乔燕,孙淼,王苇,刘春华,吴玲玉. HAG预激方案治疗低增生性急性髓细胞白血病临床研究[J]. 世界中西医结合杂志, 2011, 6(3): 222-224
作者姓名:韩乔燕  孙淼  王苇  刘春华  吴玲玉
作者单位:靖江市人民医院,江苏,靖江,214500
摘    要:目的探讨HAG预激方案对低增生性急性髓细胞白血病患者的临床疗效及不良反应。方法对28例低增生性急性髓细胞白血病(AML)患者采用HAG预激方案化疗,监测临床症状、体征、血常规及骨髓细胞形态学检查。结果 28例患者中第1个疗程完全缓解15例,第2个疗程完全缓解5例,3例部分缓解,4例未缓解,1例治疗中死于脑出血;1个疗程完全缓解率53.6%,总疗程完全缓解率71.4%,总有效率82.1%。外周血WBC低于1.0×109/L的中位时间为7.2(1~16)d。结论 HAG预激方案治疗低增生性AML近期疗效显著,不良反应轻,患者耐受性较好,且有利于减轻患者的经济负担,有一定的临床推广价值。

关 键 词:预激方案  急性髓细胞性白血病  粒细胞集落刺激因子

Clinical Research of HAG Priming Induction Regimen for the Treatment of Low Proliferative Acute Myeloid Leukemia
HAN Qiao-yan,SUN Miao,WANG Wei,LIU Chun-hua,WU Ling-yu. Clinical Research of HAG Priming Induction Regimen for the Treatment of Low Proliferative Acute Myeloid Leukemia[J]. World Journal Of Integrated Traditional and Wesrern Medicine, 2011, 6(3): 222-224
Authors:HAN Qiao-yan  SUN Miao  WANG Wei  LIU Chun-hua  WU Ling-yu
Affiliation:HAN Qiao-yan,SUN Miao,WANG Wei,LIU Chun-hua,WU Ling-yu(Jingjiang Municipality People's Hospital,Jingjiang Jiangsu 214500)
Abstract:Objective To explore the clinical efficacy and adverse reaction of HAG priming induction regimen for the treatment of low proliferative acute myeloid leukemia(AML).Methods 50 cases of low proliferative AML were treated with chemotherapy of HAG priming induction regimen.The clinical symptoms,physical signs,blood routine and morphologic examination of bone marrow and cells were monitored.Results Of 28 cases,15 cases were released completely after the 1st session of treatment,5 cases were released completed af...
Keywords:Priming induction regimen  Acute myeloid leukemia(AML)  Granulocyte colony stimulating factor  
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