A novel triterpenoid saponin from Polygala tenuifolia Willd |
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| Authors: | Tun-Hai Xu Gang Lv Ya-Juan Xu Sheng-Xiu Xie Hong-Feng Zhao Dong Han Yun-Shan Si Yu Li Jian-Zhao Niu Dong-Ming Xu |
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| Institution: | Department of Traditional Chinese Medicine Chemistry, School of Traditional Chinese Medicine, Beijing University of Chinese Medicine, Beijing, China. |
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| Abstract: | A new triterpenoid saponin, tenuifoside A, was isolated together with three known triterpenoid saponins 2, 3, and 4 from the roots of Polygala tenuifolia Willd. With the help of chemical and spectral analyses (IR, MS, 1D-NMR, and 2D-NMR), the structure of the new saponin was elucidated as 3-O-beta-d-glucopyranosyl presenegenin 28-O-beta-d-xylopyranosyl-(1 --> 3)-beta-d-xylopyranosyl-(1 --> 4)-beta-d-apiofuranosyl-(1 --> 3)]-alpha-l-rhamnopyranosyl-(1 --> 2)-4-O-p-methoxycinnamoyl]-alpha-l-rhamnopyranosyl-(1 --> 3)]-beta-d-fucopyranosyl ester (1). Three known triterpenoid saponins (2-4) were identified on the basis of spectroscopic data. |
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