Flow cytometry as a tool to determine the effects of cell wall-active antibiotics on vancomycin-susceptible and -resistant Enterococcus faecalis strains |
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| Authors: | Chau Françoise Lefort Agnès Benadda Samira Dubée Vincent Fantin Bruno |
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| Affiliation: | EA3964, Faculté de Médecine Xavier Bichat, Université Paris 7, Paris, France. |
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| Abstract: | Flow cytometry and confocal microscopy were used to study the effects of vancomycin, daptomycin, telavancin, and PA1409, a new investigational vancomyquine, on the morphology, membrane potential, and permeability of glycopeptide-susceptible and -resistant Enterococcus faecalis strains. Daptomycin exerted the most pronounced effects on bacterial size and bacterial permeability against susceptible and resistant strains. |
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