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福州市生活饮用水及其水源水有机提取物的体内遗传毒性研究
引用本文:郑能雄,徐幽琼,王春兰,林华影,柯华,林侃,肖明发.福州市生活饮用水及其水源水有机提取物的体内遗传毒性研究[J].癌变.畸变.突变,2010,22(6):452-454.
作者姓名:郑能雄  徐幽琼  王春兰  林华影  柯华  林侃  肖明发
作者单位:福州市疾病预防控制中心,福建,福州,350004
基金项目:福州市科学计划项目(2008-G-119)
摘    要:目的:探讨福州市生活饮用水及其水源水的体内遗传毒性。方法:随机选择福州市5个区县(市)各1家水厂,采集水源水和出厂水各200 L,经XAD-2树脂柱收集其中的有机物,采用小鼠骨髓细胞微核试验和精子畸形试验检测其遗传毒性。结果:长乐市、平潭县水厂出厂水和水源水及福清市水厂出厂水具有致突变性;各出厂水有机提取物的致突变性基本高于同厂水源水。结论:福州市部分生活饮用水水源水和出厂水受到一定程度的有机物污染。

关 键 词:生活饮用水  有机提取物  体内遗传毒性

In vivo genetic toxicity of organic extractions from drinking and source water in Fuzhou
ZHENG Neng-xiong,XU You-qiong,WANG Chun-lan,LIN Hua-ying,KE Hua,LIN Kan,XIAO Ming-fa.In vivo genetic toxicity of organic extractions from drinking and source water in Fuzhou[J].Carcinogenesis,Teratogenesis and Mutagenesis,2010,22(6):452-454.
Authors:ZHENG Neng-xiong  XU You-qiong  WANG Chun-lan  LIN Hua-ying  KE Hua  LIN Kan  XIAO Ming-fa
Institution:ZHENG Neng-xiong,XU You-qiong,WANG Chun-lan,LIN Hua-ying,KE Hua,LIN Kan,XIAO Ming-fa(Fuzhou Center for Disease Control , Prevention,Fuzhou 350004,Fujian,China)
Abstract:OBJECTIVE: To evaluate the in vivo genotoxicity of drinking and source water in Fuzhou.METHODS: Five districts were randomly chosen in Fuzhou with a water plant in every district.200 liters drinking water and source water were sampled in every district.XAD-2 resin was used to extract the organic matter in water,and mouse bone marrow micronucleus and sperm abnormality test were used to detect the genotoxicity of the organic extractions.RESULTS: The drinking and source water of water plants in Changle city an...
Keywords:drinking water  organic extractions  in vivo genotoxicity  
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