原发性乳腺癌经皮病灶穿刺组织病理学检查临床应用研究

目的评价超声影像与徒手引导方式对原发性乳腺癌经皮病灶穿刺组织病理学检查结果可靠性的影响,探讨病灶穿刺组织病理学检查在目前原发性乳腺癌治疗中的应用价值。方法回顾性分析697例原发性乳腺癌经皮乳腺病灶穿刺组织病理学检查结果以及临床资料。结果本研究中病灶穿刺组织病理学阳性率90．5％、假阴性率8．9％、可疑癌占0．6％。超声影像引导368例,徒手引导329例;2组中T0期与T1期病灶所占比例分别为17．9％和18．2％（P〉0．05）,超声影像引导与徒手引导的确诊率分别为92．7％和88．2％（P〈0．05）,假阴性率分别为7．1％和10．9％（P〉0．05）。结论对可触及的乳腺癌病灶进行经皮病灶穿刺组织病理学检查,超声影像引导或徒手引导都为可靠的方式。超声影像引导方式的叮靠性优于徒手引导方式。

Clinical study of percutaneous ultrasound-guided or freehand core needle biopsy of primary breast cancer

Objective To evaluate ultrasound-guided or freehand percutaneous core needle biopsy in histopathological assessment of primary breast cancer lesions and its utility in primary breast cancer treatment.Methods Retrospectively analysis of the clinical data of 697 primary breast cancer examined by mean of core needle biopsy.Results The diagnostic accuracy,false negative rate and insufficiency rate was 90.5%,8.9% and 0.6%,respectively.Diagnostic accuracy was significantly higher in ultrasound guiding comparing to palpable guiding(92.7% vs.88.2%,P<0.05).There was a nonsignificant trend toward increased false negative rate in palpable guiding(10.9% vs.7.1%,P>0.05).Conclusion(Percutaneous core) needle biopsy is reliable in histopathological assessment of primary breast cancer lesions.Ultrasound guiding was superior to palpable guiding in term of diagnostic accuracy in this study.