CONGENITAL NEPHROTIC SYNDROME DETECTED BY HYPOTHYROID SCREENING |
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Authors: | J T FINNEGAN E J SLOSBERG D C POSTELLON W A PRIMACK |
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Institution: | The Borgess Medical Center, Kalamazoo, Michigan, USA and the Department of Pediatrics, Wayne State University School of Medicine, Children's Hospital of Michigan, Detroit, Michigan, USA |
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Abstract: | Abstract. Finnegan, J., Slosberg, E., Postellon, D. and Primack, W. (Borgess Medical Center, Kalamazoo, Michigan and Children's Hospital of Michigan, Wayne State University School of Medicine, Detroit, Michigan, USA). Congenital nephrotic syndrome detected by hypothyroid screening. Acta Pediatr Scand, 69: 705, 1980.—An infant was evaluated for a low thyroxine value, detected on routine neonatal screening for congenital hypothyroidism. She was found to have the congenital nephrotic syndrome, and to be euthyroid with low thyroid binding globulin. Congenital nephrosis can be detected by neonatal screening programs which use thyroxine as the primary screening test, but not by those which use TSH. This may be important in those countries in which the incidence of congenital nephrosis approaches that of congenital hypothyroidism. |
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Keywords: | Thyroid screening hypothyroidism congenital nephrosis thyroxine thyroid stimulating hormone thyroid binding globulin |
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