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HPLC测定呋喃西林脚气粉中呋喃西林的含量
引用本文:陈京海,郭春. HPLC测定呋喃西林脚气粉中呋喃西林的含量[J]. 药学与临床研究, 2001, 9(4): 20-21
作者姓名:陈京海  郭春
作者单位:江苏省药品检验所,南京210008
摘    要:采用高效液相色谱法,以C18柱,水-乙腈-三乙胺缓冲液(82:17:1)为流动相,对呋喃西林进行了线性,实验回收率和辅料干扰实验,并定量测定呋喃西林脚气粉中呋喃西林的含量,该方法不需预先分离,其精密度与准确度良好。

关 键 词:呋喃西林脚气粉 呋喃西林 HPLC法 含量测定
收稿时间:2001-05-30

Determination of Nitrofurazone in Nitrofurazone Powder for Beriberi by HPLC
Chen Jinghai and Guo Chun. Determination of Nitrofurazone in Nitrofurazone Powder for Beriberi by HPLC[J]. Pharmacertical and Clinical Research, 2001, 9(4): 20-21
Authors:Chen Jinghai and Guo Chun
Abstract:A highly selective HPLC method for the determination of nitrofurazone in nitrofurazone powder for beriberi was described. Mobile phase is a filtered and degassed mixture of water, acetonitrile and triethylamine buffer (82:17:1). The liquid chromatograph is equipped with a 365 nm detector and a C18 column. The flow rate is about 1.5 ml per minute. The results obtained are satisfactory all in linearity, recovery and excipient interference.
Keywords:Nitrofurazone   HPLC   Determination of content
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