乌鲁木齐某社区维吾尔族、汉族人群甲状腺结节和肥胖的相关性研究

目的 探讨乌鲁木齐市某社区维吾尔族（维族）、汉族人群甲状腺结节与肥胖的关系。方法 对乌鲁木齐市某社区2 080例社区居民进行甲状腺疾病流行病学调查，选取资料完整的2 068例研究对象进行问卷调查、人体指标测量和甲状腺超声检测。结果 甲状腺结节的检出率为27.6%，维（27.4%）、汉（27.8%）两民族间差异无统计学意义（χ2=0.027，P=0.869）；肥胖的检出率为30.0%，维族中的检出率（38.9%）高于汉族（21.1%），差异有统计学意义（χ2=77.818，P<0.001）；腹型肥胖的检出率为66.6%，维族中的检出率（70.2%）高于汉族（63.0%），差异有统计学意义（χ2=12.224，P<0.001）。肥胖者与腹型肥胖者中甲状腺结节的检出率均高于非肥胖者与非腹型肥胖者（均有P<0.001）。多因素Logistic回归分析显示，总人群中高龄、女性、超重及肥胖是甲状腺结节的独立危险因素（均有P<0.05）；在男性及女性中分别显示，高龄、腹型肥胖是甲状腺结节的独立危险因素（均有P<0.05）。结论 本研究人群甲状腺结节、肥胖及腹型肥胖检出率偏高。高龄、女性、超重及肥胖、腹型肥胖人群是甲状腺结节的高危人群。

Study on the correlation between thyroid nodules and obesity in Uyghur and Han nationalities in a community population of Urumqi

Objective To explore the relationship of thyroid nodules and obesity among Uygur and Han residents in a community of Urumqi.Methods A total of 2 068 community residents were investigated through questionnaires,medical examinations,and thyroid B ultrasound.Results The detection rate of thyroid nodule in this population was 27.6％,there was no significant difference (x2 =0.027,P =0.869) between Uyghur(27.4％) and Han nationality (27.8％);The detection rate of obesity was 30.0％,the prevalence was higher in Uyghur(38.9％) than Han nationality(21.1％),which has statistical significance (x2 =77.818,P ＜ 0.001);The detection rate of abdominal obesity was 66.6％,the prevalence was higher in Uyghur(70.2％) than Han nationality (63.0％),which has statistical significance (x2 =12.224,P ＜ 0.001).The detection rate of thyroid nodule was higher in people with obesity and abdominal obesity rather than non-obesity and non-abdominal obesity (all P ＜ 0.001).Logistic regression analysis showed that older age,female,overweight and obesity were independent risk factors of thyroid nodule in the total population(all P ＜ 0.05).Respectively in male and female showed that older age,abdominal obesity were independent risk factors of thyroid nodule (all P ＜0.05).Conclusions The detection rate of thyroid nodules,obesity and abdominal obesity is higher in the study population.Older age,female,overweight,obesity,and abdominal obesity are high-risk groups of thyroid nodule.