无功能胰岛细胞瘤19例诊断与治疗

目的：探讨无功能胰岛细胞瘤的诊断和治疗。方法：回顾分析19例患者的病史资料，其中施行肿瘤摘除5例，胰体尾切除＋脾切除5例，胰十二指肠切除2例，胰体尾切除＋Roux-en-Y吻合术1例，全胰切除1例，胆囊空肠吻合术3例，活检2例。结果：肿瘤位于胰头6例，胰体2例，胰尾9例，累及全胰2例，多发1例；病理证实恶性8例，良性11例。除2例术后分别死亡肝功能衰竭和胰瘘、多器官衰竭外均获满意疗效。结论：手术切除肿瘤均可取得良好疗效。

The Diagnosis and Therapy of 19 Cases Nonfunctioning Islet Cell Tumor

Objective:To study the diagnosis and treatment of nonfunctioning islet cell tumor retrospectively. Methods:The nineteen cases with nonfunctioning islet cell tumor from 1968 to 1999 year in the First Affiliated Hospital of Nanjing Medical University were studied, with a mean of 32.3 years (range, 7~53). CT, B US, ERCP, MRI and the barium meal of upper Gastrointestinal were performed in 8,14,6,1,10 cases seperatively; and 14 patients were underwent a resection operation. There were pancreaticoduodenectomy 2 cases, distal pancreatectomy plus splenectomy 5 cases, tumor excision 5 cases, tumor excision plus ROUX EN Y anatomsis and whole pancreatectomy 1 case respectively. Results:There were 8 cases confirmed to be malignant; The mass in the head of pancreas was 6 cases, in the body 2 cases, in the tail 9 cases and in whole pancreas 2 cases. All 14 cases had a good prognosis except two cases died from the complications after operations. Conclusion:All the patients with nonfunctioning islet cell tumor ought to resect mass if can.