甘油果糖滴速对急性脑梗死患者血液流变学的影响

目的:探讨甘油果糖滴速对急性脑梗死患者血液流变学的影响。方法:采用前瞻性临床对照试验,将273例入选患者随机分为慢滴组(20%甘油果糖250mL,静脉滴注120min滴完)、快滴组(20%甘油果糖250mL,静脉滴注60min滴完),检测2组各项血液流变学指标,如全血比黏度(ηb)、全血还原比黏度(ηLr)、血浆黏度(ηp)、血细胞比容(HCT)、红细胞聚集指数(EAI)的变化并进行统计学分析。结果:急性脑梗死患者经甘油果糖治疗后各血液流变学指标均有不同程度的下降,且慢滴组的下降程度优于快速组,2组比较有显著性差异(P<0.05)。结论:甘油果糖慢滴组对改善急性脑梗死患者的血液流变学效果明显优于快滴组。

Effects of Glycerin Fructose Injection Dripping Speed on Hemorheology in Patients with Acute Cerebral Infarction

OBJECTIVE： To observe the effects of glycerin fructose injection dripping speed on hemorheology in patients with acute cerebral infarction. METHODS： A total of 273 cases were randomly assigned to slow dripping speed group and fast dripping speed group. The trend of examination indexes including whole blood viscosity （ηb）, whole blood reducing viscosity （ηLr）, plasma viscosity （ηp）, hematocrit（HCT）, erythrocyte aggregation index （EAI） of two groups were analyzed statistically using prospective clinical control trial. RESULTS： With glycerin fructose injection therapy, hemorheological indexes all decreased at different degrees; slow dripping speed group was better and statistical difference was noted in the comparison of two groups（P〈0.05）. CONCLUSION： The curative effect of glycerol fructose on the hemorheology of patients with acute cerebral infarction in slow dripping speed group is superior to in fast dripping speed group.