| IL-5 Up-regulates the Expression of TGF-β1 in Human Blood Eosinophils in Vitro |
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| 作者姓名： | 黄亚冰 刘斌 王璐 李荣 朱珉 陈栋 陈实 |
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| 作者单位： | Institute of Organ Transplantation Tongji Hospital Tongji Medical College Huzhong University of Science and Technology and the Key Laboratory of Organ Transplantation Ministry of Education and Health Wuhan 430030 China，Institute of Organ Transplantation Tongji Hospital Tongji Medical College Huzhong University of Science and Technology and the Key Laboratory of Organ Transplantation Ministry of Education and Health Wuhan 430030 China，Institute of Organ Transplantation Tongji Hospital Tongji Medical College Huzhong University of Science and Technology and the Key Laboratory of Organ Transplantation Ministry of Education and Health Wuhan 430030 China，Institute of Organ Transplantation Tongji Hospital Tongji Medical College Huzhong University of Science and Technology and the Key Laboratory of Organ Transplantation Ministry of Education and Health Wuhan 430030 China，Institute of Organ Transplantation Tongji Hospital Tongji Medical College Huzhong University of Science and Technology and the Key Laboratory of Organ Transplantation Ministry of Education and Health Wuhan 430030 China，Institute of Organ Transplantation Tongji Hospital Tongji Medical College Huzhong University of Science and Technology and the Key Laboratory of Organ Transplantation Ministry of Education and Health Wuhan 430030 China，Institute of Organ Transplantation Tongji Hospital Tongji Medical College Huzhong University of Science and Technology and the Key Laboratory of Organ Transplantation Ministry of Education and Health Wuhan 430030 China |
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| 基金项目： | This project was supported by a grant from the National Natural Sciences Foundation of China （No. 30200263）. |
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| 摘 要： | Withthedevelopmentofimmunosuppressivetherapy,therateofacuterejectioninhomotrans plantationhasdecreasedsubstantiallyinclinicalpractice.Therateoflosinggraft,however,hasincreasedatarateof3%-5%eachyear.There fore,howtoimprovethesurvivalratehasbecomeamatterofurgency.Eosinophilsareoneoftheef fectorcellsintherejectionoftransplantation.TheyareactivatedandaccumulatedbyarangeofTcell derivedcytokines.Amongthese,IL5,whichissecretedbyasubsetofhelperTcells(Th2),ismoreimportanteffective[1].Afterthetranspl…
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| 关 键 词： | IL-5 TGF-β1 基因表达 嗜酸性粒细胞 血液检查 |
| 收稿时间： | 2005-10-30 |
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