Rathke囊肿的病理与临床、影像对照分析

目的 探讨Rathke囊肿病理与临床和CT、MRI表现的相关性.方法 回顾分析经手术病理证实的Rathke囊肿43例的病理和CT、MRI表现及临床特征.结果 27例位于鞍内和鞍上,16例位于鞍内.CT平扫囊肿多呈边界清晰的"类圆形"或"哑铃"状肿物,其中9例低密度,9例高密度,8例等或稍高混杂密度,1例囊壁钙化;CT增强扫描有6例囊壁呈环形或边缘强化,其余无强化.MR检查18例T1WI呈低或等信号,T2WI呈高信号,6例T1WI和T2WI均显示高信号,4例T1WI高信号,T2WI呈混杂信号.4例囊肿内结节,T1WI呈高信号,T2WI呈低或混杂信号.MR增强检查有9例囊壁的外缘增强.术中见肿物呈囊状,10例囊液呈脑脊液样清亮液体,15例为胶冻状咖啡色黏液,12例呈豆渣样黏稠液,6例为深褐色油状黏液.组织学分析显示部分囊液中含有脂肪结晶和脱落皮屑样物,11例HE染色可见胆固醇裂隙、凝血及肉芽组织,16例PAS染色阳性,囊液内含有黏多糖和蛋白质类物质.结论 典型的Rathke囊肿术前可以明确诊断,非典型Rathke囊肿的CT、MRI表现缺乏特异性.随着囊液组织成分的变化,影像学表现有一定的变化规律.

Rathke Cleft Cysts:Comparative Study of Pathology,Clinic and Imaging

Objective To study the correlation among pathological,clinical and the imaging features(CT and MRI) of the Rathke cleft cysts.Methods CT,MRI and clinical findings of Rathke cleft cysts in 43 patients confirmed by operation and pathology were retrospectively studied.Results 27 cysts located at intrasella and suprasella and 16 cysts entirely located at intrasella.Cysts were round or oval in shape with definite borders.The size of 30 cysts exceed 10mm in diameter.On CT scans reviewed,the cysts were low density...