| 层粘连蛋白与颅内星形胶质细胞瘤分化、转移关系的探讨 |
| |
| 引用本文： | 史小林,徐庆中.层粘连蛋白与颅内星形胶质细胞瘤分化、转移关系的探讨[J].首都医学院学报,1996,17(4):267-269. |
| |
| 作者姓名： | 史小林 徐庆中 |
| |
| 作者单位： | 首都医科大学生殖医学研究室，首都医科大学宣武医院病理科 |
| |
| 摘 要： | 应用ＬＳＡＢ免疫组化法，分别对胶质母细胞瘤组和星形胶质细胞瘤组进行层粘连蛋白（ＬＮ）免疫染色。发现ＬＮ分布在血管基膜和胶质膜等部位。星形胶质细胞瘤组血管周围可见较多的双管套状结构，内侧管为血管基膜ＬＮ呈强阳性。胶质母细胞瘤组血管周围多呈多层纤维围绕状，血管基膜ＬＮ呈中等阳性。星形胶质瘤ＬＮ免疫组化显示的双层套管结构随恶性程度增高而减少。提示可利用ＬＮ免疫组化法鉴别肿瘤的恶性程度。
|
| 关 键 词： | 层粘连蛋白，星形细胞肿瘤，免疫组织化学 |
| 收稿时间： | 1995-12-23 |
The Study of the Relationship between Laminin and Intracranial Astrocytoma Differentiation and Metastasis |
| |
| Shi Xiaolin, Weng Jing, Xu Qing, Liang Yuanjing.The Study of the Relationship between Laminin and Intracranial Astrocytoma Differentiation and Metastasis[J].Journal of Capital University of Medical Sciences,1996,17(4):267-269. |
| |
| Authors: | Shi Xiaolin Weng Jing Xu Qing Liang Yuanjing |
| |
| Institution: | 1. Department of Reproductive Medicine, Capital University of Medical Sciences;2. Department of Pathology, Xuanwu Hospital, Affiliate of Capital University of Medical Sciences |
| |
| Abstract: | The distribution of laminin (LN) in astrocytoma of various stages of differentiation were observed to study the relationship between laminin and intracranial astrocytoma differentiation and metastasis. LSAB immunohistochemistry method was showed laminin. The laminin distributed mainly in the glial and vascular basement membrane. Astrocytoma show structure of ring upon ring around blood vessels. Glioblastoma show multilayer fibriosis structure.The LN reaction of the vascular basement membrane dicreased,showed positive. According to the malignancy of the tumor. |
| |
| Keywords: | laminin astrocytoma immunohistochemistry |
| 本文献已被 CNKI 维普 等数据库收录！ |
| 点击此处可从《首都医学院学报》浏览原始摘要信息 |
| 点击此处可从《首都医学院学报》下载免费的PDF全文 |
