| DSP的毒理学安全性研究 |
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| 引用本文： | 肖忠新,孔祥环.DSP的毒理学安全性研究[J].首都医学院学报,1996,17(3):205-207. |
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| 作者姓名： | 肖忠新 孔祥环 |
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| 作者单位： | 首都医科大学环境卫生教研室 |
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| 摘 要： | 对ＤＳＰ进行了急性毒性及诱变性研究。结果表明：大、小鼠经口ＬＤ_（５０）均大于６００ｍｇ／ｋｇ体重，小鼠骨髓微核试验、Ａｍｅｓ试验及小鼠精子畸形试验均为阴性，未发现有诱变性。
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| 关 键 词： | DSP 急性毒性 诱变试验 |
A Toxicological Study of DSP for Safety Evaluation |
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| Xiao Zhongxin ,Kong Xianghuan , Yin Xuejun, Wang Hong, Tang Yuping.A Toxicological Study of DSP for Safety Evaluation[J].Journal of Capital University of Medical Sciences,1996,17(3):205-207. |
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| Authors: | Xiao Zhongxin Kong Xianghuan Yin Xuejun Wang Hong Tang Yuping |
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| Institution: | Department of Environmental Health, Capital University of Medical Sciences |
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| Abstract: | The acute toxicity and mutagenic assays of DSP were carried out. The results showed that the LD50 by the oral route in mice and rats were both more than 600 mg/kg. Micronucleus test of mice bone marrow. Ames test and sperm abnormalities test in mice were all negative and mutagenicity of DSP was not discovered. |
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| Keywords: | DSP acute toxicity mutagenic assays |
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