Adhesion inhibitory activity of β-lactoglobulin isolated from infant formulae |
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| Authors: | AC Ouwehand SJ Salminen |
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| Affiliation: | Centre for Biotechnology, University of Turku, Åbo Akademi University, Turku, Finland;Department of Food Chemistry, University of Turku, Åbo Akademi University, Turku, Finland |
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| Abstract: | β-Lactoglobulin was isolated from infant formulae that were ultra high temperature (UHT) -treated, sterilized or spray-dried. The effect of the isolated β-lactoglobulin on SfaII-fimbriae-mediated adhesion of Escherichia coli to human ileostomy glycoproteins was studied in vitro. β-Lactoglobulin isolated from sterilized formulae was found to perform significantly less well than preparations from spray-dried formulae (p = 0:05). Great heterogeneity was observed in the adhesion inhibitory capacity of β-lactoglobulin isolated from UHT-treated formulae. Therefore, no significant difference was observed between UHT-treated and sterilized formulae or spray-dried formulae (p < 0:10). It can be hypothesized that β-lactoglobulin from spray-dried and some UHT-treated infant formulae may affect the colonization of mucous membranes by E. coli strains causing neonatal septicaemia and meningitis. |
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| Keywords: | Adhesion inhibition Escherichia coli infant formula β-lactoglobulin |
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