| 化瘀破癥胶囊对荷瘤小鼠化疗所致骨髓抑制的保护作用研究 |
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| 引用本文： | 曹勇,钟安朴,孟华,夏清华.化瘀破癥胶囊对荷瘤小鼠化疗所致骨髓抑制的保护作用研究[J].时珍国医国药,2006,17(3):314-315. |
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| 作者姓名： | 曹勇 钟安朴 孟华 夏清华 |
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| 作者单位： | 暨南大学医学院,广东,广州,510632 |
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| 基金项目： | 暨南大学自然科学基金资助项目(No.692001) |
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| 摘 要： | 目的探讨化瘀破癥胶囊对肿瘤化疗所致骨髓抑制的保护作用。方法以小鼠移植性Lew is肺癌为模型,分别观察化瘀破癥胶囊对环磷酰胺(Cy)所致荷瘤鼠外周血象、骨髓有核细胞数下降的变化。结果化瘀破癥胶囊能显著增加Cy所致荷瘤鼠外周血下降的白细胞数(P<0.01),以及下降的骨髓有核细胞数(P<0.01)。结论化瘀破癥胶囊对动物移植性肿瘤化疗所致骨髓抑制有保护作用。
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| 关 键 词： | 化瘀破癥胶囊 荷瘤小鼠 骨髓抑制 |
| 文章编号： | 1008-0805(2006)03-0314-02 |
| 修稿时间： | 2005年4月28日 |
Protective Effects of Huayu Pozheng Capsule on Chemotherapy Inducing Marrow Restraining in Tumor-bearing Mice |
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| CAO Yong,ZHONG An-pu,MENG Hua,XIA Qing-hua.Protective Effects of Huayu Pozheng Capsule on Chemotherapy Inducing Marrow Restraining in Tumor-bearing Mice[J].Lishizhen Medicine and Materia Medica Research,2006,17(3):314-315. |
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| Authors: | CAO Yong ZHONG An-pu MENG Hua XIA Qing-hua |
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| Abstract: | ObjectiveTo explore protective effects of Huayu Pozheng Capsule(HYPZC) on chemotherapy inducing marrow depression in tumor-bearing mice.MethodsLewis lung cancer models of transplanted mice were used,changes of tumor-bearing mice hemogram and bone marrow karyote to cyclophosphamide(Cy) of HYPZC were observed respectively.ResultsHYPZC can significantly increase tumor-bearing mice leucocyte and bone marrow karyote(P<0.01).ConclusionHYPZC has protective effects for tumor-bearing mice bone marrow depression by chemotherapy. |
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| Keywords: | Huayu Pozheng Capsule Tumor-bearing mice Bone marrow depression |
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