小儿川崎病冠状动脉病变临床分析

目的:探讨小儿川崎病患儿冠状动脉受损状况和心功能的相应改变情况。方法:应用超声心动图对81例小儿川崎病患儿.冠状动脉受伤状况予以检查,通过Cuben's方法对小儿川崎病患儿.的左心室收缩功能进行相关测定,以二尖瓣的多普勒血流图对小儿川崎病患儿.的左心室舒张功能予以测定,将81例小儿川崎病患儿.与62例正常小儿心功能状况进行对比分析。结果:在81例小儿川崎病中有35例小儿存在冠状动脉受损情况,其中24例为急性期冠状动脉扩张,5例为冠状动脉瘤,6例为恢复期冠状动脉扩张。观察组患儿VE为(86.1±27.5)cm/s,对照组为(89.1±31.7)cm/s,两组差异无统计学意义(P﹥0.05);观察组患儿VA为(47.9±13.1)cm/s,对照组为(44.9±10.1)cm/s,两组差异无统计学意义(P﹥0.05);观察组患儿心脏射血分数为0.68±0.21,对照组为0.69±0.31,两组差异无统计学意义(P﹥0.05);两组在左心室收缩功能以及左心室舒张功能方面差异无统计学意义(P>0.05)。结论:在临床中小儿川崎病通常容易累及患儿的冠状动脉,特别是在小儿川崎病的急性期;患儿的心功能改变相对不明显,临床超声心动图有助于对小儿川崎病患儿冠状动脉受损状况予以测定。

Clinical analysis on coronary arterial lesions of children with Kawasaki disease

Objective:To explore the condition of coronary arterial lesions among children with Kawasaki disease and the corresponding changes.Methods:Echocardiography was used to examine the condition of coronary arterial lesions among 81 children with Kawasaki disease,the left ventricular diastolic function was detected by Cuben′s method,Doppler blood flow spectrum of mitral valve was used to detect the left ventricular diastolic function of the children with Kawasaki disease,the cardiac functions of 81 children with Kawasaki disease and 62 normal children were compared and analyzed.Results:Among 81 children with Kawasaki disease,35 children were found with coronary arterial lesions,including 24 children with coronary artery dilatation at acute phase,5 children with coronary arterial aneurysm,6 children with coronary artery dilatation at recovery phase.VE in observation group and control group were(86.1±27.5) cm/s and(89.1 ±3.17) cm/s,respectively,there was no significant difference between the two groups(P>0.05);VA in observation group and control group were(47.9±13.1) cm/s and(44.9±10.1) cm/s,respectively,there was no significant difference between the two groups(P>0.05);the cardiac ejection fraction in observation group and control group were(0.68±0.21) and(0.69±0.31),respectively,there was no significant difference between the two groups(P>0.05);there was no significant difference in left ventricular systolic function and left ventricular diastolic function between the two groups(P>0.05).Conclusion:In clinic,Kawasaki disease often damage coronary artery of the children,especially at acute phase;the change of cardiac function is not obvious,clinical ultrasonography is helpful to detect the condition of coronary arterial lesions of children with Kawasaki disease.