布地奈德、特布他林雾化液联合雾化吸入治疗小儿毛细支气管炎疗效研究

目的:探讨布地奈德联合特布他林雾化液雾化吸入治疗小儿毛细支气管炎的临床疗效。方法:选择该院2007年3月～2010年3月收治的72例住院毛细支气管炎患儿作为观察对象,根据治疗方法的不同随机分为治疗组和对照组各36例,两组均常规给予抗感染、化痰、静滴地塞米松0.2 mg.kg-1.d-1,每天1次,双肺喘鸣音消失后改为口服强的松0.75 mg.kg-1.d-1,每天3次,同时予吸氧、镇静、补液、营养支持等治疗,治疗组在常规治疗基础上给予生理盐水1 ml/次+布地奈德雾化液0.5 mg/次+特布他林雾化液2.5 mg/次(阿斯利康有限公司生产)氧气驱动雾化吸入,氧流量为6～8 L/min,5～10 min/次,每天2次,雾化至临床症状、体征消失。比较两组的疗效及临床症状体征改善情况。结果:治疗组有效率为94.44%,对照组有效率为83.33%,两组患者疗效及有效率比较差异有统计学意义(P<0.05)。全部患者未见明显的不良反应。治疗组咳嗽、喘憋、喘鸣音及肺部啰音的消失时间明显短于对照组,且住院时间也短于对照组(P<0.05)。结论:布地奈德、特布他林溶液联合雾化吸入治疗小儿毛细支气管炎疗效确切,可以明显改善患者的临床症状,缩短住院时间,安全无痛苦,小孩易接受,值得临床推广。

Study on the curative effect of aerosol inhalation of budesonide combined with terbutaline in treatment of infantile bronchiolitis

Objective:To explore the clinical curative effect of aerosol inhalation of budesonide combined with terbutaline in treatment of infantile bronchiolitis.Methods:72 hospitalized infants with bronchiolitis who were treated in the hospital from March 2007 to March 2010 were selected as observation objects,then they were divided into treatment group and control group according to different therapies,36 infants in each group;the infants in the two groups were treated with anti-infection,resolving phlegm and intra...