| 天津市婴幼儿孤独症患病率与危险因素 |
| |
| 引用本文： | 苏媛嫒,张欣,李爱月,李义民,刘功妹. 天津市婴幼儿孤独症患病率与危险因素[J]. 中国妇幼保健, 2011, 26(32): 5004-5007 |
| |
| 作者姓名： | 苏媛嫒 张欣 李爱月 李义民 刘功妹 |
| |
| 作者单位： | 1. 天津医科大学公共卫生学院儿童少年卫生学教研室,天津,300070
2. 天津市妇女儿童保健中心 |
| |
| 基金项目： | 国家自然科学基金资助项目〔81072313〕 |
| |
| 摘 要： | 目的:探讨天津市婴幼儿孤独症的患病率及相关危险因素,为今后孤独症病因研究提供线索。方法:应用巢式病例对照研究方法,按分层整群抽样的原则随机抽取天津市7 904名1.5～3岁的儿童进行孤独症筛查,对412名筛查阳性儿童进行追踪,年龄满3岁时进行孤独症确诊;每个病例按相同性别月龄匹配4例对照,因素调查表分为四部分,每部分分别进行单因素及多因素条件Logistic回归。结果:22例确诊为孤独症,天津市婴幼儿孤独症患病率及其95%的可信区间为27.83/万(16.22/万～39.44/万),男性孤独症患病率是女性的4倍(P<0.05)。单因素分析时发现孤独症的危险因素总共有8个,各部分多因素分析显示主要危险因素为:父亲有害职业史、母亲人工流产史、被动吸烟、妊娠浮肿、妊娠呕吐、新生儿黄疸。结论:孤独症不应再被认为是极罕见病,环境因素与孤独症发病有一定关系。
|
| 关 键 词： | 婴幼儿期 孤独症 巢式病例 危险因素 |
Prevalence and risk factors of infantile autism in Tianjin |
| |
| SU Yuan-Yuan,ZHANG Xin,LI Ai-Yue et al.Public Health College of Tianjin Medical University,Tianjin ,Chian. Prevalence and risk factors of infantile autism in Tianjin[J]. Maternal and Child Health Care of China, 2011, 26(32): 5004-5007 |
| |
| Authors: | SU Yuan-Yuan ZHANG Xin LI Ai-Yue et al.Public Health College of Tianjin Medical University Tianjin Chian |
| |
| Affiliation: | SU Yuan-Yuan,ZHANG Xin,LI Ai-Yue et al.Public Health College of Tianjin Medical University,Tianjin 300070,Chian |
| |
| Abstract: | Objective:To investigate the prevalence and related risk factors of infantile autism in Tianjin,in order to provide clues to etiology of autistic disorder.Methods:Using nested case-control study,7 904 children aged 1.5 to 3 were screened for autistic disorder by cluster random sampling method,412 screening-positive children entered the cohort and were diagnosed when they were 3 years old.4 healthy children were selected to match 1 case,with the same age and sex.The screen and diagnostic questionnaire used i... |
| |
| Keywords: | Infants and young children Autistic disorder Nested case-control study Risk factors |
| 本文献已被 CNKI 万方数据 等数据库收录！ |
|
