颈动脉粥样硬化斑块与血浆纤维蛋白原的关系

目的探讨患者颈动脉粥样硬化程度以及颈动脉粥样硬化性质与血浆纤维蛋白原的关系。方法对存在颈动脉粥样硬化的65例患者进行颈动脉彩色多普勒检查,记录颈动脉粥样硬化斑块的部位、回声强度、颈总动脉分叉处内膜中层厚度及血管内径,并根据颈动脉狭窄程度分为4组,再根据超声检查动脉硬化斑块性质分为硬斑和软斑2组,同时检测血浆纤维蛋白原水平,进行统计学分析。结果随着血浆纤维蛋白原水平的升高,动脉粥样硬化狭窄程度也随之增加,且呈正相关;中、高浓度纤维蛋白原组软斑发生率明显多于低浓度组。结论血浆纤维蛋白原水平与颈动脉粥样硬化斑块的性质有关,血浆纤维蛋白原可能决定了颈动脉粥样硬化斑块稳定性。而且血浆纤维蛋白原升高与颈动脉粥样硬化密切相关,可能在颈动脉粥样硬化的发生发展中起着重要的作用。

Relationship between Carotid Atherosclerotic Plaque and Plasma Fibrinogen

Objective]To study the relationship between carotid atherosclerosis and plasma fibrinogen.Methods]Color Doppler was carried out on carotid artery of 65 carotid atherosclerotic patients,recording position,echo intensity of artherosclerotic plaque,carotid artery intima-media thickness and vessel inside diameter.According to carotid artery stenosis,the patients were divided into 4 groups,and were re-divided into 2 groups(hard plaque and soft plaque) on the basis of character of atherosclerotic plaque,meanwhi...