急性N-甲基吡咯烷酮中毒的临床分析

目的分析急性N-甲基吡咯烷酮中毒(N-methy1-2-pyrrolidone,N-MP)的临床特点,发现早期诊断及治疗方法。方法收集17例职业性急性N-MP中毒病例临床资料,包括症状、体征及实验室检查结果,将其进行综合分析。结果职业性急性N-MP中毒的临术特点以消化系统损害为主要表现,其中腹痛较为突出,伴有丙氨酸转氨酶(ALT)、天冬氨酸转氨酶(AST)、乳酸脱氢酶(LDH)升高。结论诊断应基于明确的N-MP接触史、现场调查、临床表现及实验室结果,同时对N-MP中毒的临床表现规律应做进一步研究。

Clinical Analysis of Acute N-MP Poisoning

Objective] To analyze the clinical characteristics of acute N-Methy1-2-Pyrrolidone (N-MP)poisoning,and identify the early diagnosis and treatment.Methods]Clinical data of 17 cases of acute N-MPpoisoning were collected,including symptoms,physical signs and laboratory findings for comprehensive analysis.Results]The main characteristics of N-MP posioning were digestive system impairment,especially abdominal pain,with high levels of ALT,AST and LDH.Conclusion]Diagnosis should base on the definite history of...