经微导管局部灌注无水乙醇治疗肝癌高流量性动静脉瘘

目的：探讨经微导管血管内局部灌注无水乙醇栓塞治疗肝癌动静脉瘘的可行性及临床疗效。方法：对29例肝癌患者动静脉瘘血管分别应用微导管行超选择性插管局部灌注无水乙醇，造影观察动静脉瘘闭塞情况及对非靶血管的影响。结果：29例肝癌患者共发现41支动静脉瘘血管，单支血管局部灌注无水乙醇1-6次，2-3ml/次，总量2-12ml。造影示瘘管全部闭塞，非靶血管保持通畅，随后经导管动脉化疗栓塞（TACE）碘油沉积满意，临床症状明显好转或消失。结论：应用微导管局部灌注无水乙醇可安全有效地治疗肝癌动静脉瘘，为肝癌TACE治疗创造有利条件。

Transmicrocatheter local injection of ethanol to treat hepatocellular carcinoma with high flow arteriovenous shunts

Objective To evaluate the feasibility and clinical effect of embolization therapy in treating the high flow hepatic arteriovenous shunts in hepatocellular carcinoma (HCC) by locally injected ethanol through microcatheter. Methods Forty-one branches of arteriovenous shunts were treated by local ethanol infusion through microcatheter in 29 patients suffered with HCC. Angiography was performed to observe the embolization effect and influence to non-targeted vessels. Result Forty-one branches of arteriovenous shunts in 29 patients were injected with ethanol locally. Each single shunt was infused 1-6 times. The dose of ethanol was 2-3 ml per time, and the total dose of ethanol was 2-12 ml. All shunting tracts were embolized, and all non-target vessels were protected fluently. Iodine-oil deposition was well in continued TACE. Their syndromes were improved or disappeared. Conclusion Transmicrocatheter injection of ethanol could safely and effectively treate the hepatic arteriovenous shunts and make advantages to TACE in HCC.