CT小肠造影对活动性克罗恩病的诊断价值

目的:本研究的目的是确定CT小肠造影(CT enterography,CTE)检查对活动性克罗恩病诊断价值。方法:回顾性分析58例确诊克罗恩病患者。男性47例,女性11例,平均年龄53.5岁。所有病例行小肠CTE检查。扫描范围从膈顶至盆腔。由2位不知道病理结果的放射科医生共同观察确定有无病变,病灶部位,累积肠段数目,肠壁厚度,肠壁强化,肠腔狭窄,肠外淋巴结,肠系膜水肿及血管改变,肠外炎症,瘘管及瘘道等,判断病变是否具有活动性。并将CTE检查结果与临床症状及内镜检查比较。结果:58例克罗恩病以回肠末端为最常见受累部位(54/58),小肠单独受累(48/58),小肠-结肠受累(10/58)。肠壁增厚(51/58)。累积肠段数目(107段)、肠壁厚度(3.2~21.5)mm,动脉期肠壁强化(56.2~89.4)HU静脉期(87.6~103.8)HU、肠腔狭窄(55/58)、肠外淋巴结(32/58)、肠系膜水肿及血管改变(50/58)、肠外炎症、瘘管及瘘道等(3/58)。临床症状及内镜检查证实的活动期患者51例,稳定期患者7例。2位医生诊断活动性克罗恩病阳性48例,3例稳定期病例误认为活动期。CTE诊断克罗恩病活动期的敏感度、特异度、阳性预测值及阴性预测值分别为(94%,48/51)、(40%,2/5)、(96%,48/50)、(38%,3/8)。结论:CT小肠造影对活动期克罗恩病诊断具有较高的价值,确诊还应结合临床及肠镜检查。CT小肠造影对早期克罗恩病诊断作用还有待研究。

The value of diagnosis of active Crohn disease with CT enterography

Objective:The purpose of our study was to determine the value of diagnosis of active Crohn disease(CD) with CT enterography(CTE).Methods:In 58 patients(11 women,47 men;mean age,53.5 years) with known Crohn disease were retrospectively evaluated.All patients underwent CT enterography examination,scanning filed including abdomen and pelvis.two radiologists who were unknow the clinical history blinded interpreted imagings.They determined whether imaging findings of Crohn disease were present,lesion site,number...