体外线圈磁共振波谱分析在前列腺病变诊断中的价值

目的:探讨采用体外线圈进行三维磁共振波谱分析(three dimensional magnetic resonance spectroscopy,3DMRS)检查在前列腺病变诊断中的价值。方法:分析19例前列腺癌、26例前列腺增生患者的3D MRS资料,采用One-way ANOVA检验对前列腺癌、前列腺增生及正常前列腺外周叶Cho+Cr/Cit(CC/C)平均比值进行统计学分析,比较是否具有统计学差异性。结果:前列腺癌、前列腺增生及正常前列腺外周叶CC/C平均比值分别为2.58±1.61,0.57±0.25,0.36±0.18。前列腺癌与前列腺增生、正常前列腺外周叶组间的差异有显著统计学意义(F=211.338,P<0.01)。结论:体外线圈进行前列腺3D MRS能够较好的检出前列腺病变中的代谢物,并有助于前列腺疾病的诊断及鉴别诊断。

The value of three-dimensional magnetic resonance spectroscopy on prostatic disease with external coil

Objective：To evaluate the value of three dimensional magnetic resonance spectroscopy（3D MRS） on prostate with external coil.Methods：3D MRS data of 19 patients with prostate cancer and 26 patients with prostatic hyperplasia were analyzed,Differentiation of Cho＋Cr/Cit（CC/C） among prostate cancer,prostatic hyperplasia and normal peripheral leaves were tested by means of one-way ANOVA statistics.Results：The average ratio of CC/C for prostate cancer（2.58±1.61） was statistically higher than that of prostatic hyperplasia（0.57±0.25） and normal peripheral leaves（0.36±0.18）（F=211.338,P0.01）.Conclusion：3D MRS on prostate with external coil can detected the diseased prostate metabolites,can be used in diagnosis and differential diagnosis of prostate disease.