| 血管环模型的研究进展 |
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| 引用本文： | 李秋影. 血管环模型的研究进展[J]. 医学综述, 2011, 17(3): 339-342 |
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| 作者姓名： | 李秋影 |
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| 作者单位： | 天津中医药大学,天津,300193;天津天士力研究院药理毒理所,天津,300410 |
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| 摘 要： | 血管环模型在新药筛选和病理生理基础研究中占有重要地位。目前血管环的研究类型主要包括两大类:血管收缩活性研究和血管生成活性研究。血管收缩活性研究涉及的疾病领域宽广,包括高血压、脑供血不足、充血性心力衰竭等。血管生成活性研究则主要集中在抗肿瘤研究和动静脉吻合的研究上。随着新技术和新思路的引进,血管环实验在相关领域的新药研发、基础研究等方面发挥着重要的作用。
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| 关 键 词： | 血管环 血管收缩 血管生成 |
Review of Study on Vascular Ring |
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| LI Qiu-ying. Review of Study on Vascular Ring[J]. Medical Recapitulate, 2011, 17(3): 339-342 |
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| Authors: | LI Qiu-ying |
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| Affiliation: | LI Qiu-ying1,2,LI Xin-xin2,ZHOU Wang-yi2,MO Hong-mei2,GUO Zhi-xin2.(1.Traditional Chinese Medicine University of Tianjin,Tianjin 300193,China,2.Department of Pharmacology and Toxicology of Tasly Institute,Tianjin 300410,China) |
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| Abstract: | Main study on vascular ring could depart in two aparts,one for vascular contractility,the other for angiogenesis.The study for vascular contractility was used in variety fields including hypertension,cerebrovascular insufficiency syndrome pulmonary hypertension congestive heart failure shock etc.And anti-tumer research is the main field of angiogenesis study.Vascular ring study play an important role in new drug founding and in basic research. |
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| Keywords: | Vascular ring Contractility Angiogenesis |
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