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The Expression and Significance of SOCS-1/3 in Rats with Experimental Myocardial Ischemia/reperfusion Injury |
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| Authors: | Guo Tangmeng Yang Qunfang Liu Chengyun Cheng Bei Huang Lili Liu Cunfei |
| Institution: | Guo Tangmeng,Yang Qunfang,Liu Chengyun,Cheng Bei,Huang Lili,Liu Cunfei.Department of Geriatrics,Union Hospital of Huazhong University of Science and Technology,Hubei 430022,China |
| Abstract: | Objective To investigate the expression and significance of SOCS-1/3 in rats with experimental myocardial ischemia/reperfusion injury.Methods The model of rats with experimental myocardial ischemia/reperfusion injury was established.The expression of SOCS-1/3 and inflammatory cytokines mRNA in myocardial ischemia/reperfusion group(MIR) and sham group was evalunated with RT-PCR analysis.Results The expression of two kinds of inflammatory cytokines(interferon-alpha and interleukin-6) mRNA was increased on the... |
| Keywords: | SOCS-1/3 Inflammatory cytokine Ischemia reperfusion injury |
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