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| 正畸牙移动造成大鼠牙周S-100表达改变的实验研究 | |
| 引用本文： | 鹿蕾,王美青,刘晓东,于世宾. 正畸牙移动造成大鼠牙周S-100表达改变的实验研究[J]. 医学研究杂志, 2011, 40(4): 27-30 |
| 作者姓名： | 鹿蕾 王美青 刘晓东 于世宾 |
| 作者单位： | 第四军医大学口腔医学院口腔解剖生理学教研室及颞下颌关节病科,西安,710032 |
| 基金项目： | 国家自然科学基金资助项目 |
| 摘 要： | 目的研究正畸牙移动及其引起的咬合变化对大鼠牙周组织中施万细胞标志物S-100表达的影响。方法 8周龄雌性SD大鼠,实验组用正畸皮圈推左上和右下第3磨牙向远中,建立大鼠正畸牙移动模型,空白对照组不进行任何操作。应用免疫组织化学方法检测左上第3磨牙(移动牙)和右上第3磨牙(正畸移动牙的对颌牙,简称对颌牙)远中根牙周组织内S-100的表达变化。结果对照组牙周S-100阳性结构主要集中在牙根中下1/3的远中牙周膜中,移动牙于正畸操作3天后出现S-100阳性结构的增多和聚集,对颌牙则于正畸操作后14天出现S-100阳性结构的增多和聚集,S-100阳性结构增多均伴有血窦的增多。移动牙和对颌牙的上述改变都于28天时恢复至对照组水平。结论正畸移动不仅可以造成移动牙,而且可以造成移动牙的对颌牙牙周施万细胞标志物S-100的一过性增多和聚集,以及血窦增多。 |
| 关 键 词： | 正畸牙移动 咬合紊乱 施万细胞 S-100免疫组织化学 |
| 收稿时间： | 2010-12-09 |
Expression Changes in Periodontium of Rats Induced by Orthodontic Tooth Movement |
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| Lu Lei,Wang Meiqing,Liu Xiaodong,Yu Shibin. Expression Changes in Periodontium of Rats Induced by Orthodontic Tooth Movement[J]. Journal of Medical Research, 2011, 40(4): 27-30 | |
| Authors: | Lu Lei Wang Meiqing Liu Xiaodong Yu Shibin |
| Affiliation: | Lu Lei,Wang Meiqing,Liu Xiaodong,Yu Shibin.Department of Oral Anatomy and Physiology and Temporomandibular Joint Disorder,School of Stomatology,Fourth Military Medical University,Shanxi 710032,China |
| Abstract: | Objective To study the effects of the orthodontic tooth movement and disordered occlusion on the S-100 marked Schwann cells in the periodontium of rats.Methods Orthodontic tooth movement was established in 8-week-old female SD rats.The left maxillary and right mandibular third molars were pushed distally by an elastic band.No procedure was performed on the control animals.The changes of S-100 expression in distal root of both the left maxillary third mol ar(the moving tooth) and the right maxillary third mo... |
| Keywords: | Orthodontic tooth movement Disordered occlusion Schwann cells S-100 Immunohistochemistry |
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