| Abstract: | Changes in the ultrastructure of the blood-testis barrier in rats 30 and 60 min and 1 and 30 days after ligation of the testicular artery were studied by electron microscopy. The results showed that blocking of the blood flow to the testis causes rapidly progressive changes in all components of the blood-testis barrier. Micropinocytosis and destructive changes increase in the cytoplasm of the endotheliocytes of the capillaries, ending in microclasmatosis. The tunica propria of the seminiferous tubules is highly sensitive to ischemia. It becomes thickened, the nuclei and cytoplasmic organoids of its cellular components are deformed, and folding and infiltration of the basement membrane increase. Vacuolation of the cytoplasm of the sustentocytes is accompanied by destruction of the cell membrane and by separation of the sustentocytes from the tunica propria of the tubules.Department of Human Anatomy, Ivano-Frankovsk Medical Institute. (Presented by Academician of the Academy of Medical Sciences of the USSR A. P. Avtsyn.) Translated from Byulleten' Éksperimental'noi Biologii i Meditsiny, Vol. 88, No. 8, pp. 223–226, August, 1979 |
