| 碘普罗胺致急性肾衰竭 |
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| 引用本文： | 胡云珍,卢晓阳.碘普罗胺致急性肾衰竭[J].药物不良反应杂志,2011,13(3):183-184. |
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| 作者姓名： | 胡云珍 卢晓阳 |
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| 作者单位： | 浙江大学医学院附属第一医院药剂科,杭州,310006 |
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| 摘 要： | 1例65岁男性2型糖尿病患者,因反应迟钝伴口齿不清入院。头颅磁共振成像示脑梗死(急性期),给予肠溶阿司匹林(0.1g,1次/d)、依达拉奉(30mg,1次/d)及甲钴胺等药物治疗。因胸部、腹部CT增强扫描,连续2d各使用造影剂碘普罗胺100ml(含碘30g),第3天出现双下肢水肿,尿量400ml/24h,随后无尿,静脉给予呋塞米未见好转。复查血肌酐475μmol/L,尿素氮24.5mmol/L。诊断为急性肾衰竭,考虑与碘普罗胺有关。连续血液透析治疗5d后,患者尿量增加,血肌酐降至284μmol/L。17d后血肌酐231μmol/L,尿素氮14.4mmol/L。患者双下肢水肿明显好转,出院。
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| 关 键 词： | 碘普罗胺 急性肾衰竭 |
Iopromide-induced acute renal failure |
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| Hu Yunzhen,Lu Xiaoyang.Iopromide-induced acute renal failure[J].Adverse Drug Reactions Journal,2011,13(3):183-184. |
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| Authors: | Hu Yunzhen Lu Xiaoyang |
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| Institution: | Hu Yunzhen,Lu Xiaoyang~*(Department of Pharmacy,First Affiliated Hospital,College of Medicine,Zhejiang University,Hangzhou 310006,China) |
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| Abstract: | A 65-year-old man with type 2 diabetes mellitus was hospitalized with slow response to stimuli and slurred speech. Cranial magnetic resonance imaging showed cerebral infarction(acute phase).He was treated with enteric-coated aspirin 0.1 g once daily,edaravone 30 mg once daily,methylcobalamin,etc.He received the contrast medium iopromide 100 ml(equivalent to 30 g iodine) once daily for two days for undergoing contrast-enhanced CT scans of lung and abdomen.On day 3,he developed lower extremity edema,his 24 ho... |
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| Keywords: | iopromide acute renal failure |
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