多层羊膜移植在角膜穿孔伤中的应用研究

目的评价多层羊膜移植在角膜穿孔伤后修复缺损组织的效果。方法通过对7例单眼角膜穿孔，创口有缺损或感染糜烂，难以一期密闭缝合者行多层羊膜移植术。术后随访平均14个月。结果7眼中6眼（85．71％）角膜穿孔创口瘢痕愈合，前房恢复，眼前段稳定；1眼因眼内感染严重，羊膜融解而摘除眼球。结论对伴有角膜组织缺损或糜烂的较小的角膜穿孔伤，当无法行常规缝合或无条件行穿透性角膜移植术时，多层羊膜移植术，是可行的。

Multilayer amniotic membrane transplantation for corneal penetrating injury

Objective To evaluate the effect of multilayer amniotic membrane transplantation for repairing the corneal tissue defect after corneal penetrating injury.Methods There were 7 cases (7 eyes) of corneal penetrating injury with corneal tissue defect or with infection of wound,which could not be sewed in regular methods.Multi-layer amniotic membrane transplantation were applied for them.They were followed up for an average of 14 months.Results 6 cases ( 85.71％ ) of corneal perforating resulted in wound healing,anterior chamber restoration,and stable anterior segment; One patient with severe infection in the eye,the amniotic membrane dissolved and the eyeball was enucleated.Conclusion For the smaller corneal penetrating injury patients with corneal tissae defect or wound infection,a multilayer anmiotic membrane transplantation is an effective and feasible surgical approach.