Sinus bradycardia associated with daclizumab in liver transplant recipients: report of 3 cases |
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Authors: | Bassily-Marcus Adel Kohli-Seth Roopa Leibowitz Andrew Murgolo Victor Oropello John Manasia Anthony Benjamin Ernest |
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Affiliation: | Department of Surgery, Division of Critical Care Medicine, The Mount Sinai School of Medicine, New York, NY 10029, USA. adel.bassily-marcus@mssm.edu |
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Abstract: | Daclizumab is a commonly used immunosuppressive agent for prophylaxis of solid organ rejection. Although rare, the cardiovascular adverse effects of daclizumab include sinus tachycardia, hypotension, and hypertension. Here, we report 3 patients who developed significant and prolonged sinus bradycardia after receiving daclizumab following orthotopic liver transplant. Daclizumab should be considered a possible cause of bradycardia following its administration in orthotopic liver transplant. |
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