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Chronic rhinosinusitis in elderly patients is associated with an exaggerated neutrophilic proinflammatory response to pathogenic bacteria
Authors:Justin C. Morse  Ping Li  Kim A. Ely  Meghan H. Shilts  Todd J. Wannemuehler  Li-Ching Huang  Quanhu Sheng  Naweed I. Chowdhury  Rakesh K. Chandra  Suman R. Das  Justin H. Turner
Affiliation:1. Department of Otolaryngology–Head and Neck Surgery, Vanderbilt University Medical Center, Nashville, Tenn;2. Department of Pathology, Microbiology, and Immunology, Vanderbilt University Medical Center, Nashville, Tenn;3. Department of Medicine, Vanderbilt University Medical Center, Nashville, Tenn;4. Department of Biostatistics, Vanderbilt University Medical Center, Nashville, Tenn
Abstract:
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  • Keywords:Rhinosinusitis  aging  cytokine  neutrophil  bacteria  endotype  inflammation  IL-1β  CRS  Chronic rhinosinusitis  CT  Computed tomography  OR  Odds ratio  SIT  Smell Identification Test  SNOT-22  22-Item Sinonasal Outcome Test
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