Human bocavirus infection in children with acute respiratory tract infection in India |
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| Authors: | Preeti Bharaj Wayne M. Sullender Sushil K. Kabra Shobha Broor |
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| Affiliation: | 1. Department of Microbiology, All India Institute of Medical Sciences, Ansari Nagar, New Delhi, India;2. Department of Pediatrics and Infectious Diseases, University of Alabama at Birmingham, Birmingham, Alabama;3. Department of Pediatrics, All India Institute of Medical Sciences, Ansari Nagar, New Delhi, India |
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| Abstract: | Human bocavirus (HBoV) is a new human parvovirus identified in children with respiratory tract disease. Nasopharyngeal aspirates were collected from 305 children <5 years of age with acute respiratory tract infection from April 2005 to March 2007 and screened for the presence of HBoV by two separate sets of a polymerase chain reaction (PCR) described previously. Twenty‐two (7.2%) children who had acute respiratory infection were found to be positive for HBoV by both sets of PCR. The main clinical symptoms were cough (95%), runny nose (64%), and fever (59%). In two samples, HBoV was identified together with respiratory syncytial virus in one sample and influenza A virus in another. HBoV appeared to have no seasonal distribution and is associated with both upper and lower respiratory tract disease in young children in India. J. Med. Virol. 82: 812–816, 2010. © 2010 Wiley‐Liss, Inc. |
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| Keywords: | human bocavirus acute respiratory infections polymerase chain reaction clinical symptoms |
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