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The SQ tree SLIT-tablet is highly effective and well tolerated: Results from a randomized,double-blind,placebo-controlled phase III trial
Authors:Tilo Biedermann  Piotr Kuna  Petr Panzner  Erkka Valovirta  Morgan Andersson  Frederic de Blay  Dorthe Thrane  Sanja Hald Jacobsen  Brian Sonne Stage  Lone Winther
Institution:1. Department of Dermatology and Allergology, Technical University of Munich, Munich, Germany;2. Division of Internal Medicine, Asthma and Allergy, Barlicki University Hospital, Medical University of Lodz, Lodz, Poland;3. Department of Immunology and Allergology, Faculty of Medicine in Pilsen, Charles University, Prague, Czech Republic;4. Department of Pulmonary Diseases and Clinical Allergology, University of Turku, Turku, Finland;5. Terveystalo Allergy Clinic, Turku, Finland;6. Department of Otorhinolaryngology, Head and Neck Surgery, Skåne University Hospital, Lund, Sweden;7. Federation of Translational Medicine Chest Disease Department, University Hospital of Strasbourg, University of Strasbourg, Strasbourg, France;8. Global Clinical Development, ALK-Abelló, Hørsholm, Denmark;9. Allergy Clinic, Department of Dermato-Allergology, Gentofte Hospital, Copenhagen, Denmark
Abstract:
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  • Keywords:Allergic rhinoconjunctivitis  allergy immunotherapy  birch pollen  clinical efficacy  clinical trial  safety  sublingual immunotherapy tablet  total combined score  tree pollen  AE  Adverse event  ARC  Allergic rhinoconjunctivitis  BPS  Birch pollen season  DMS  Daily medication score  DSS  Daily symptom score  EAACI  European Academy of Allergy and Clinical Immunology  ICH  International Conference on Harmonisation  RQLQ  Rhinoconjunctivitis Quality of Life Questionnaire  RQLQ(S)  Rhinoconjunctivitis Quality of Life Questionnaire with Standardized Activities  SLIT  Sublingual immunotherapy  TCS  Total combined score (sum of rhinoconjunctivitis DSS and DMS)  TPS  Tree pollen season
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