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心电图对兔急性心肌梗死的诊断价值
引用本文:孙林 光雪峰 李易 张戈 徐章. 心电图对兔急性心肌梗死的诊断价值[J]. 云南医药, 2006, 27(1): 6-8
作者姓名:孙林 光雪峰 李易 张戈 徐章
作者单位:[1]昆明医学院第二附属医院心血管内科,云南省冠心病基础研究室,云南昆明650101 [2]云南省第二人民医院心脏中心内科,云南昆明650021
摘    要:目的 探讨心电图对兔急性心肌梗死(AMI)的诊断价值。方法 无菌条件下开胸结扎兔冠状动脉左前降支(LAD),建立急性心肌梗死动物模型,观察术前、术后即刻、1/2小时(h)、1h、2h和6周的心电图(ECG)变化特点,并结合心肌酶学及病理检查结果判断兔AMI模型是否成功。结果 术前描记常规导联ECG均正常,术后ECG最显著的变化为:心率减慢,R波振幅降低,T波高尖。胸导联ST段抬高及病理性Q波出现。结论 术后心率减慢及R波振幅降低可作为早期诊断兔AMI的可靠指标。

关 键 词:急性心肌梗死 心电描记术 兔
文章编号:1006-4141(2006)01-0006-03
收稿时间:2005-07-08

Study on the value of electrocardiogram in diagnosing acute myocardial infarction of rabbit
SUN Lin, GUANG Xue - feng, LI Yi,et al.. Study on the value of electrocardiogram in diagnosing acute myocardial infarction of rabbit[J]. Medicine and Pharmacy of Yunnan, 2006, 27(1): 6-8
Authors:SUN Lin   GUANG Xue - feng   LI Yi  et al.
Affiliation:SUN Lin, GUANG Xue - feng, LI Yi, et al.
Abstract:Objective To investigate the value of electrocardiogram(ECG) in diagnosing acute myocardial infarction(AMI) of rabbit.Methods A rabbit model of AMI was made by opening chest and ligating the left anterior descending(LAD) coronary artery.ECG was observed before operation,immediate after,half an hour,1h,2h and 6 weeks after LAD ligation.ECG combined with myocardial enzyme and pathologic histology were used to judge the success of the model of AMI.Results ECG was normal before operation.After LAD ligation,the heart rates of rabbits turned slowly,R waves decreased,T waves rose,ST segments ran up in chest leads and abnormal Q waves appeared.Conclusion The heart rates of rabbits turned slowly and R waves decreased after operation,which can be used to judge the AMI model success.
Keywords:Acute myocardial infarction    Electrocardiogram    Rabbit
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