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血清CTn-I和Hs-CRP联合检测在冠心病中的应用价值
引用本文:招钜泉,谢冰,袁程伟.血清CTn-I和Hs-CRP联合检测在冠心病中的应用价值[J].中国当代医药,2010,17(22):60-61.
作者姓名:招钜泉  谢冰  袁程伟
作者单位:广东省佛山市南海区桂城医院检验科,广东佛山,528000
摘    要:目的:评估血清CTn-I和Hs-CRP联合检测在冠心病中的应用价值。方法:检测96例确诊为冠心病患者和30例健康对照者血清中CTn-I和Hs-CRP水平,分析冠心病患者中稳定性心绞痛、不稳定性心绞痛以及心肌梗死3个亚组人群中的血清CTn-I和Hs-CRP水平。结果:冠心病患者血清CTn-I和Hs-CRP明显高于健康对照者(P〈0.05),稳定性心绞痛和不稳定性心绞痛患者血清CTn-I升高不明显,但Hs-CRP已明显升高,而血清CTn-I和Hs-CRP在心肌梗死组升高最明显(P〈0.05),Spearman等级相关分析提示随着冠心病严重程度升高,血清CTn-I和Hs-CRP逐渐升高。结论:联合检测冠心病患者血清CTn-I和Hs-CRP将有利于对患者病情的评估。

关 键 词:肌钙蛋白-I  高敏C-反应蛋白  冠心病

The significance of combination detection of cardiac troponin-I and high sensitivity C-reaction protein of coronary artery disease
Authors:ZHAO Juquan  XIE Bing  YUAN Chengwei
Institution:(Department of clinical laboratory,Guicheng Hospital of Nanhai District of Foshan City,Guangdong Province,Foshan 528000,China)
Abstract:Objective: To evaluate the serum CTn-I and Hs-CRP combined detection value in coronary artery disease.Methods: 96 patients diagnosed with coronary artery disease detected patients and 30 healthy controls serum CTn-I and Hs-CRP levels of coronary heart disease patients with stable angina pectoris,unstable angina and myocardial infarction in three sub-group of people in the serum CTn-I and Hs-CRP levels.Results: The serum levels of CTn-I and Hs-CRP was significantly higher than healthy controls(P〈0.05),stable angina and unstable angina patients CTn-I increase was not obvious,but the Hs-CRP was significantly elevated,while serum CTn-I and Hs-CRP increased in the MI group,the most significant(P〈0.05),Spearman rank correlation analysis showed that the severity of coronary heart disease with increased serum CTn-I and Hs-CRP gradually increased.Conclusion: The detection of coronary heart disease patients CTn-I and Hs-CRP will contribute to the assessment of patient condition.
Keywords:Troponin-I  High-sensitivity C-reactive protein  Coronary heart disease
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