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Detection of human papillomavirus DNA in an ameloblastoma using the in situ hybridization technique |
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| Authors: | W. F. P. van Heerden E. J. van Rensburg E. J. Raubenheimer E. H. Venter |
| Affiliation: | Department of Oral Pathology and Oral Biology, Medical University of Southern Africa, South Africa;Department of Medical Virology, University of Pretoria, South Africa;Department of Infectious Diseases, Faculty of Veterinary Science, University of Pretoria, South Africa |
| Abstract: | HPV type 18 DNA was identified in an intrabony ameloblastoma using radio-labelled in situ hybridization. The viral DNA was found in a verrucous lesion in a cystic area of the tumor. The absence of HPV DNA in other epithelial areas of the ameloblastoma is suggestive of a secondary infection. HPV is not considered to be an etiological factor in the pathogenesis of this ameloblastoma. |
| Keywords: | ameloblastoma DNA human papillomavirus type 18 in situ hybridization |