右室收缩时间间期观察新生儿肺血液动力学变化

本文测定72例出生6日内,健康新生儿的右室收缩时间间期(RSTI),其中22例出生24小时内的新生儿并进行了吸高浓度氧(5L/min)前后的对比。吸氧前后及不同日龄间三组RSTI各参数的比较,都有显著或非常显著的差异,主要表现为RPEP缩短、RVET延长、RPEP/RVET及RICT/RVET比值减小,反映右室后负荷下降。RPEP/RVET、RICT/RVET比值与新生儿日龄的关系,经双曲线回归分析,呈负相关,P<0.01,二者曲线都于24小时内下降最迅速,其次为2～4日,符合健康新生儿生理性肺高压下降的规律,因而上述比值可以作为研究肺血管病的参考,用以系统观察,自我对比,有利于某些心脏病手术时机的选择及术后随访。

THE CHANGES OF PULMONARY HEMODYNAMIICS NEONATAL RSIT

The right ventricular systolic intervals(RSTI)in health neonates were determined in 72 cases within 6 days after delivery. The RSTI of 22 neonates were compared with before and after inspirated oxygen of high concentration (5 1/min.) within 24 hrs after delivery. Every paremeter of RSTI in each group was contrasted with those of other group in differnt times(or days)The main appearances were significantly,such as shortness of RPEP, prologation of RVET, RPEP/RVET and RICT/RVET decreased.It showed that the right ventricular load was decreased.The ratio among RPEP/RVET, RICT/RVET and neonatal daily age was minus relationship by double curve regression analysis(p<0.01).The curve fell down sharply within 24 hrs, then 2nd to 4th days.According to the rule, the neonatal physiological pulmonary hypertension was decreased. The ratio mentioned above may referred to the pulonary vascular bed studies. It is advantageous to the selection of cardiac operation time and the postoperatiove patient.follow up