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红曲霉液体培养法制备姜黄素的工艺优化
引用本文:潘婕,申莉娟,徐戡. 红曲霉液体培养法制备姜黄素的工艺优化[J]. 中国实验方剂学杂志, 2013, 19(13): 51-53
作者姓名:潘婕  申莉娟  徐戡
作者单位:中北大学化工与环境学院,太原,030051
摘    要:目的:优选红曲霉液体培养法制备姜黄素的工艺条件.方法:以天然姜黄为原料,姜黄素得率为指标,在单因素试验基础上,采用正交试验考察发酵时间、料液比、营养比和发酵液pH对制备工艺的影响.结果:最佳制备工艺为发酵时间5d,料液比1 g·L-1,营养比1/6,发酵液pH 4,姜黄素得率达0.43%.结论:优选的制备工艺稳定可行、效率高.

关 键 词:红曲霉  姜黄素  液体培养  发酵  显著性
收稿时间:2012-11-21

Optimization of Preparation Technology for Curcumin by Monascus Liquid Culture Method
PAN Jie,SHEN Li-juan and XU Kan. Optimization of Preparation Technology for Curcumin by Monascus Liquid Culture Method[J]. China Journal of Experimental Traditional Medical Formulae, 2013, 19(13): 51-53
Authors:PAN Jie  SHEN Li-juan  XU Kan
Affiliation:School of Chemical Engineering and Environment, North University of China, Taiyuan 030051, China;School of Chemical Engineering and Environment, North University of China, Taiyuan 030051, China;School of Chemical Engineering and Environment, North University of China, Taiyuan 030051, China
Abstract:Objective:To optimize preparation technology of curcumin by monascus liquid culture method. Method: With natural Curcuma longa as raw materials and yield of curcumin index,based on single-factor tests,effect of solid-liquid ratio,fermentation time,nutrition ratio and pH of fermentation broth on preparation technology was investigated by orthogonal test. Result: Optimum preparation technology was as following:solid-liquid ratio of 1 g·L-1,fermentation time 5 d,nutrition ratio 1/6,pH of fermentation broth 4.Yield of curcumin was up to 0.43%. Conclusion: This optimized technology was stable and feasible with high efficiency.
Keywords:monascus  curcumin  liquid culture  fermentation  significant
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