| 舒脑胶囊的制备工艺研究 |
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| 引用本文： | 李平,任军,李红卫,魏琴,张金平.舒脑胶囊的制备工艺研究[J].中国药师,2006,9(9):802-803. |
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| 作者姓名： | 李平 任军 李红卫 魏琴 张金平 |
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| 作者单位： | 1. 兰州大学第二医院药剂科,兰州,730030
2. 兰州大学药学院 |
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| 基金项目： | 甘肃省中医药管理局资助项目 |
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| 摘 要： | 目的:优选舒脑胶囊制备工艺。方法:以总多糖的收率为考察指标,应用L_9(3~4)正交试验法优选舒脑胶囊的制备工艺。结果:水煎煮乙醇沉淀制备工艺影响因素依次是:乙醇沉淀浓度(D)>水煎时间(A)>水煎次数(B)>加水量(C),最佳制备工艺为A_2B_2C_1D_2,即加10倍量水,煎煮2次,每次1．5 h,乙醇沉淀浓度为50％。结论:该优选制备工艺合理,有效成分提出率高。
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| 关 键 词： | 舒脑胶囊 制备工艺 多糖 正交试验 |
| 文章编号： | 1008-049X（2006）09-0802-02 |
| 收稿时间： | 2006-02-15 |
| 修稿时间： | 2006年2月15日 |
Study on the Preparing Procedure of Shu'nao Capsules |
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| Li Ping,Ren Jun,Li Hongwei,Wei Qin,Zhang Jinping.Study on the Preparing Procedure of Shu''nao Capsules[J].China Pharmacist,2006,9(9):802-803. |
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| Authors: | Li Ping Ren Jun Li Hongwei Wei Qin Zhang Jinping |
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| Abstract: | To optimize the preparing procedure for Shunao capsules. Method: The total polysaccharides were used as index, the optimum extracting conditions were studied by the orthogonal test of L_9 ( 3~4). Result: The influencing effects of factor were as follows; D>A>B>C(A: decocting time, B: decocting frequency, C: adding water volume, D: alcohol concentration). The opti-mizing preparation conditions were A_2B_2C_1D_2, i. e. added 10 times water, decoction for twice, 1.5 h every time. The precipitating concentration of alcohol was 50%. Conclusion: The optimum preparation procedure is reliable and the extracting rate of active compo-nent is high. |
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| Keywords: | Shunao capsules Preparing procedure Polysaccharides Orthogonal test |
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